Integrated Screening of Genetic Anomalies

Aim of the study and Material and methods: Study has retrospectively evaluated 598 pregnant women, which have been controlled in our unit, since 1st of June 2003 up till now. Biochemical evaluation of markers for trisomies: free beta subunit of chorionic gonadotophine hormone (hCG) and plasma associated placental protein A (PAPP-A) was applied during first trimester of every pregnancy. Results: Considering first trimester screening, combination of risk according to patient's age and levels of biochemical markers found 39 (6.52%) abnormal biochemical screening results suggested Down syndrome, while 7 (1.17%) resu…