Dietary intake of vitamin K and risk of incident and fatal myocardial infarction in the EPIC-Heidelberg cohort study
K Nimptsch, S Rohrmann, J Linseisen, R Kaaks · Das Gesundheitswesen · 2010 · Heft 09
Bibliografische Angaben
Zusammenfassung
Background: The vitamin K-dependent Matrix-Gla-protein (MGP) has been shown to inhibit vascular calcification. Few prospective studies have been conducted relating habitual dietary vitamin K intake to the risk of coronary events. We investigated the association between phylloquinone (vitamin K1) and menaquinones (vitamin K2) intake and the risk incident and fatal myocardial infarction (MI) in the Heidelberg cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC). Methods: The study was conducted in 23,464 EPIC-Heidelberg participants aged 35–64 years and free of prevalent coronary heart…