Serum 25-hydroxy-vitamin D3 in chronic liver disease: a transient elastography- based study
K Hochrath, M Krawczyk, B Obermayer-Pietsch, M Trauner, F Lammert, F Grünhage · Zeitschrift für Gastroenterologie · 2011 · Heft 01
Bibliografische Angaben
Zusammenfassung
Background: Low serum 25-hydroxy-vitamin D3 (vit. D) levels have been associated with advanced liver fibrosis and unfavorable outcome of chronic viral hepatitis C (HCV) treatment. Lately, transient elastography (TE) has gained wide acceptance as a non-invasive tool to assess liver fibrosis. Here we investigate serum vit. D levels in relation to TE values in patients with different types of chronic liver diseases (CLD). Methods: We determined the serum vit. D concentration in 787 patients with CLDs of mixed etiologies. The HCV group included patients with viral replication (n=491), therapy non-responders (n=133)…