Prognostic impact of liver function in cystic fibrosis patients undergoing lung transplantation

Aims: Cystic fibrosis (CF) is a life-threatening autosomal recessive hereditary disease that impacts the function of multiple organ systems. In end stage disease lung transplantation has become a viable option to improve the quality of life and prolong survival. CF liver disease (CFLD) as comorbidity develops in 8–17% of CF patients with unknown impact on prognosis of lung transplantation. Methods: 31 patients with cystic fibrosis who underwent double lung transplantation (DLTx) from 1999 to 2009 in our clinic were included in the retrospective study. Posttransplant survival was assessed and liver parameters (AS…