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Sleep, sleep deprivation and immune functions – Aktuelle Themen in der Psychoneuroimmunologie

T Lange · Psychotherapie Psychosomatik Medizinische Psychologie · 2011 · Heft 02

Dokument
976189
CareLit-ID
Jahr
2011
Publikation
PDF
nein
Metadaten
DOI
ja
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Bibliografische Angaben

Zeitschrift
Psychotherapie Psychosomatik Medizinische Psychologie
Autor:innen
T Lange
Ausgabe
Heft 02 / 2011
Seiten
–
Erschienen: 2011-02-15 00:00:00
ISSN
0937-2032
DOI
10.1055/s-0031-1272403

Zusammenfassung

Sleep regulates immune functions. The first half of nocturnal sleep in humans is predominated by slow wave sleep (SWS) that serves memory and recovery functions. In addition, slow wave sleep and the circadian system act in concert to enhance the release of growth hormone (GH) and prolactin and to suppress the release of cortisol and catecholamines. This unique endocrine milieu existing around midnight facilitates the production of pro-inflammatory cytokines like interleukin (IL)–12 by stimulated monocytes and dendritic cell precursors. GH, prolactin and IL–12 are endogenous adjuvants that promote T helper (Th) 1…

Schlagworte

Antigen presenting cells Sleep T cells circadian cytokines immune Psychotherapie Psychosomatik Medizinische Psychologie