Mirror Movements in Amyotrophic Lateral Sclerosis

Objective: It was the aim of the study to investigate the occurrence of mirror movements (MM) and callosal dysfunction in amyotrophic lateral sclerosis (ALS) which have not been studied systematically till yet. Methods: 26 ALS patients (9 women, mean age of 62.6±8.8 y.) were studied by investigation of MM and transcranial magnetic stimulation (TMS) with evaluation of the ipsilateral silent period (iSP). The revised ALS Functional Rating Scale (ALFRS-R) was assessed and MM were quantified by a score from 0 to 4 in an intentional unimanual repetitive finger-tapping and -sequencing task while having the opposite ar…