The impact of the xSPECT reconstruction algorithms on the recovery coefficients value for small tumors: a phantom study with 177Lu
Ali Ebrahimifard, Hossein Rajabi, Parham Geramifar, Markus Luster, Behrooz Hooshyar Yousefi, Robin de Nijs · Nuklearmedizin - NuclearMedicine · 2025 · Heft 02 · S. 132-140
Bibliografische Angaben
Zusammenfassung
Abstract Aim Quantifying small tumors is still a challenge due to the partial volume effect (PVE). Although iterative reconstruction had promising results with a better recovery coefficient (RC), it suffers from the PVE. RC values typically depend on the reconstruction method, which may affect on 177Lu quantifying. In this study, we investigated the effect of different reconstruction methods on RC values for 177Lu SPECT/CT images. Methods A water-filled cylindrical polymethylmethacrylate (PMMA) phantom without background radioactivity with two solid cylinders which represent the bone and soft tissue equivalent w…