Outcomes of 68Ga-NODAGA-Exendin-4 PET/CT Guided Surgical Management of Insulinomas in MEN1: A Preliminary Study
Anurag Lila, Anima Sharma, Rohit Barnabas, Manjiri Karlekar, Saba Samad Memon, Vijaya Sarathi, Sameer Rege, Priyanka Verma, Gaurav Malhotra, Vikram Lele, Tushar Bandgar · Nuklearmedizin - NuclearMedicine · 2025 · Heft 05 · S. 301-307
Bibliografische Angaben
Zusammenfassung
AbstractThe data on the use of 68Ga-NODAGA-exendin-4 PET/CT in localizing multiple endocrine neoplasia type 1 (MEN1)-related insulinomas is evolving; however, surgical outcomes data are not available. We describe our cohort of patients with MEN1-related endogenous hyperinsulinemic hypoglycemia (EHH), where 68Ga-NODAGA-exendin-4 PET/CT was used to guide conservative surgery. A retrospective record review of MEN1-related EHH cases managed between 2000 and 2024 was performed for clinical features, imaging, and management. Outcomes were assessed for patients whose surgical extent was determined by 68Ga-NODAGA-exendi…