Diagnostic Performance of 99 mTc-Sestamibi SPECT/CT and 18F-Choline PET/CT in Locating Hyperfunctioning Parathyroid Glands in Patients with Primary Hyperparathyroidism
Ante Mandic, Ivana Kraljevic, Tanja Skoric Polovina, Karin Zibar Tomsic, Tina Dusek, Annemarie Balasko, Mirsala Solak, Darko Kastelan · Nuklearmedizin - NuclearMedicine · 2025 · Heft 05 · S. 308-312
Bibliografische Angaben
Zusammenfassung
Abstract Objective This study aimed to assess the diagnostic performance of 99mTc-sestamibi SPECT/CT and 18F-choline PET/CT in detecting hyperfunctioning parathyroid glands in patients undergoing surgery for primary hyperparathyroidism (PHPT). Methods A retrospective analysis was conducted on patients who underwent PHPT-related surgery between April 2019 and May 2022. The study focused on patients undergoing either 99mTc-sestamibi SPECT/CT (81 patients) or 18F-choline PET/CT (33 patients) scans before surgery to pinpoint hyperfunctioning parathyroid gland(s). In the majority of patients, 18F-choline PET/CT was p…