Primary Tumor Localization is Associated with Progression-free Survival and Overall Survival after Selective-Internal-Radio-Therapy of Liver Metastases in Metastatic Colorectal Ca…
Lucia Lutat, Barbara Kreppel, Milka Marinova, Ingo G. H. Schmidt-Wolf, Carsten Meyer, Markus Essler · Nuklearmedizin - NuclearMedicine · 2026 · Heft 01 · S. 13-21
Bibliografische Angaben
Zusammenfassung
Abstract Aim This retrospective study aimed to investigate whether the differing biology of right-sided primary tumors (RSP) and left-sided primary tumors (LSP) in metastatic colorectal cancer (mCRC) affects survival outcomes following selective internal radiation therapy (SIRT). Methods A cohort of 140 mCRC patients with liver metastases treated with SIRT between 2009 and 2016 was analyzed. Patients were stratified by tumor localization (RSP: proximal colon; LSP: distal colon and rectum), clinical, histopathological, and molecular data, were collected. Survival outcomes (OS and PFS) were evaluated using Kaplan-…