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177Lu-based radioligand therapy: A retrospective multicenter analysis to calculate the effective half-life and follow-up dose for the public

Christian Schütze, Markus Borowski, Martin Freesmeyer, Robert Freudenberg, Heribert Hänscheid, Jens Kurth, Marc Rudi Linde, Lara-Christiane Militzer, Bernhard Sattler, Tabea Nikola Schmidt, Paul Soubiran, Mathias Steffner, Lars Stegger, Carsten Wanke, Christi… · Nuklearmedizin - NuclearMedicine · 2026 · Heft 02 · S. 60-68

Dokument
976992
CareLit-ID
Jahr
2026
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Nuklearmedizin - NuclearMedicine
Autor:innen
Christian Schütze, Markus Borowski, Martin Freesmeyer, Robert Freudenberg, Heribert Hänscheid, Jens Kurth, Marc Rudi Linde, Lara-Christiane Militzer, Bernhard Sattler, Tabea Nikola Schmidt, Paul Soubiran, Mathias Steffner, Lars Stegger, Carsten Wanke, Christi…
Ausgabe
Heft 02 / 2026
Jahrgang 65
Seiten
60-68
Erschienen: 2026-04-01 00:00:00
ISSN
0029-5566

Zusammenfassung

AbstractThe study investigated routinely used radiopharmaceuticals containing lutetium-177 (177Lu), providing reference values for their effective half-life (T1/2,eff). So far, no guidelines regarding discharging this patients exist, are essential to ensure radiation protection of the public. This study contributes to the development of binding discharge criteria regarding 177Lu therapies.This retrospective multicenter study comprised eight nuclear medicine departments. Two commercially available products and two in-house preparations were considered. Radiation measurement methods, in terms of measuring device,…

Schlagworte

177Lu radioligand therapy effective half-life Radiation protection Dose rate measurement PSMA RRT Nuklearmedizin - NuclearMedicine