The influence of removal of primary tumor on incidence and phenotype of circulating tumor cells in primary breast cancer
FA Taran, A Hartkopf, M Banys, N Krawczyk, S Becker, J Jakubowska, A Stäbler, D Wallwiener, R Rothmund, T Fehm · Geburtshilfe und Frauenheilkunde · 2011 · Heft 08
Bibliografische Angaben
Zusammenfassung
Introduction: Recent studies have shown that the detection of circulating tumor cells (CTC) pre- and postoperatively in the peripheral blood of primary breast cancer patients may be an indicator for poor survival. This study aimed to investigate the influence of removal of the primary tumor on incidence and phenotype of circulating tumor cells in primary breast cancer. Methods: 209 primary breast cancer patients could be included into this analysis. Blood sampling was performed both pre- and postoperatively. The blood specimens were immunomagnetically enriched using AdnaTest BreastCancerSelect within 4 hours aft…