The Pediatric Brain Tumor Preclinical Testing Program: evaluation of an individualized molecular treatment approach

Pediatric brain tumors remain the most challenging diseases in pediatric oncology in terms of mortality. The concept of individualized treatment in cancer is highly promising, although still a vision of the future. The Pediatric Brain Tumor Preclinical Testing Program aims at the evaluation of the clinical benefit and of the feasibility of such an individualized approach. To this aim, we will include all available pediatric brain tumors independent of the histological diagnosis from seven pediatric oncology centers. All tumors will be subjected to molecular analyis by array-comparative genomic hybridization (aCG…