Impact assessment of [18F]FDG PET/CT in predicting EGFR gene mutation status in patients with lung adenocarcinoma using recovery coefficient-based correction of semi-quantitative…
Aleksei Leontev, Angelina Lokhova, Aleksandr Khalimon, Malika Khodzhibekova, Tatyana Lazutina, Gulnara Khamadeeva, Daria Khodakova, Irina Pylova, Vitaly Bobrov, Leila Atakishieva, Natalia Kadymova, Anastasia Nikiforuk, Bogdan Shvets, Nadezhda Volchenko, Vikto… · Nuklearmedizin - NuclearMedicine · 2026 · Heft 03 · S. 199-206
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Zusammenfassung
Abstract Aim The aim of this study was to assess the impact of [18F]FDG PET/CT in predicting EGFR gene mutation status in patients with lung adenocarcinoma using recovery coefficient-based (RC-based) correction of semi-quantitative and volume-based PET metrics. Methods A retrospective multi-center study included 63 patients diagnosed with lung adenocarcinoma who underwent [18F]FDG PET/CT. Acquisition was performed according to the EANM guidelines using two EARL-accredited PET/CT-systems. All patients were divided into an EGFR-mutant (n=30) and a wild-type (n=33) groups based on the results of molecular testing.…
