Baseline FDG PET/CT–Defined Axillary Burden Predicts Axillary Pathologic Complete Response After Neoadjuvant Therapy in Breast Cancer
Mehmet Tarık Tatoğlu, İlker Nihat Ökten, Ebru Ibisoglu, Tuçe Söylemez Akkurt, Ferda Yerdelen Tatoğlu, Hatice Uslu, Hakan Baysal · Nuklearmedizin - NuclearMedicine · 2026 · Heft 03 · S. 207-216
Bibliografische Angaben
Zusammenfassung
Abstract Aim Predicting axillary pathologic complete response (pCR) after neoadjuvant systemic therapy (NST) may enable risk-adapted axillary management in clinically node-positive breast cancer (BC), but practical baseline PET-derived predictors are limited. Methods Single-center retrospective cohort of consecutive cN+, M0 patients with baseline [18F]FDG PET/CT–reported axillary nodal metastasis treated with NST and surgery (complete-case n=115). Axillary pCR was defined as no residual invasive carcinoma in axillary lymph nodes; isolated tumor cells and/or micrometastases were classified as non-pCR. Two prespec…
