Comprehensive phenotyping of natural killer cells in acute and chronic viral hepatitis
S Lunemann, DFG Malone, V Schlaphoff, MP Manns, JK Sandberg, M Cornberg, HG Ljunggren, NK Björkström, H Wedemeyer · Zeitschrift für Gastroenterologie · 2013 · Heft 01
Bibliografische Angaben
Zusammenfassung
Background: Natural Killer (NK) cells play an important role in the protection against hepatitis virus infections and thought to be involved in the pathogenesis of chronic liver disease. Some studies suggested distinct effects of HBV and HCV on NK cells. In this study we aimed to elucidate the phenotype and function of NK cells in both acute and chronic viral hepatitis. Methods: Blood samples from a total of 134 individuals were studied including patients with hepatitis delta, acute hepatitis B, chronic hepatitis B, acute hepatitis C and chronic hepatitis C (n=34, 13, 25, 12, 18, respectively). 32 healthy blood…
