Rare complication of inflammatory bowel diseases: Non-Hodgkin lymphoma occurring in Crohn's disease

Introduction: It is widely known that several types of malignant disease may develop in inflammatory bowel disease (IBD) patients. The most common of these is colorectal cancer, the risk of which is proportional to the duration of the disease. The majority of the lymphomas occurring in IBD patients develop following immunomodulating or immunosuppressive treatment. Lymphoma occurring as a consequence of immunomodulating treatment has already become a well known disease entity while lymphomas developing after biological therapy were evaluated in several studies during recent years. Primary extranodal lymphomas dev…