Lungenkarzinom
N.N. · DMW - Deutsche Medizinische Wochenschrift · 2014 · Heft 11 · S. 545-556
Bibliografische Angaben
Zusammenfassung
Abstract Lung cancer is histologically classified as small cell (SCLC) and non-small cell lung cancer (NSCLC). NSCLC cancer is subclassified as squamous cell carcinoma, adenocarcinoma and large cell carcinoma. Activating EGFR mutations and EML4-ALK translocation are relevant in NSCLC, especially in non-squamous tumours. This pathological classification, as well as patient condition (performance status, functional limitations and comorbidities) and stage of disease, guides the management of these patients. Surgery, radiotherapy and systemic therapy using platinum-based chemotherapy doublets are the main stay of t…