Positive Predictors for GERD and therapeutic response to proton-pump inhibitors
V Becker, S Grotz, C Schlag, S Nennstiel, B Haller, RM Schmid, A Meining, M Bajbouj · Zeitschrift für Gastroenterologie · 2013 · Heft 09
Bibliografische Angaben
Zusammenfassung
Background: Gastroesophageal reflux disease (GERD) is one of the most prevalent gastrointestinal disorders. Most effective therapy in GERD are proton pump inhibitors (PPIs). Rates on therapeutic response are still conflicting and vary depending on reported symptoms. Aim of our study is to identify objective and subjective predictors for reliable diagnosis of GERD and response to PPI-therapy. Methods: Retrospectively, 683 consecutive patients suspected for GERD who underwent pH metry/impedance measurement (pH/MII) were analyzed. All patients had previous standard PPI treatment (e.g. pantoprazole 40 mg/day or comp…
