Valuable use of 3D in early and late 1st trimester fact or (still) fiction?

Purpose: The advent of novel US technologies has markedly improved our capabilities of early assessment of embryonic and fetal anatomy throughout the first trimester of pregnancy. In particular, three-dimensional reconstruction of normal and abnormal conceptions has given valuable insights into early human development. We herein demonstrate the potential of novel volume ultrasound applications in aiding the diagnosis of first trimester structural anomalies. Material and methods: All cases in which early embryonic demise had been confirmed and the CRL was reproducibly > 20 mm (n = 51) as well as all fetuses ≤14 c…