Early Experience With Less Invasive Surfactant Administration Under Heated Humidified High-Flow Nasal Cannula in Preterm Infants: An Observational Pilot Study
Melek Büyükeren, Tolga Celik, Sule Yigit, Murat Yurdakok · Zeitschrift für Geburtshilfe und Neonatologie · 2026 · Heft 07
Bibliografische Angaben
Zusammenfassung
Abstract Background Less invasive surfactant administration (LISA) is commonly performed under nasal continuous positive airway pressure (CPAP). Evidence regarding its use under heated humidified high-flow nasal cannula (HHHFNC) support is limited. Objective To describe the feasibility of performing LISA under ongoing HHHFNC support and to explore short-term physiological observations compared with nasal CPAP in preterm infants. Methods This observational pilot study was conducted in a tertiary neonatal intensive care unit between January and December 2017. Preterm infants with respiratory distress syndrome requ…