Frequency domains of resting state default mode network activity in schizophrenia
G Mingoia, K Langbein, M Dietzek, G Wagner, S Smesny, S Scherpiet, R Maitra, JR Reichenbach, C Gaser, H Sauer, I Nenadic, RGM Schlösser · Klinische Neurophysiologie · 2014 · Heft 03
Bibliografische Angaben
Zusammenfassung
Introduction: Recent studies have demonstrated altered low-frequency BOLD signal fluctuations during resting state (RS) in schizophrenia. It is unclear whether this alteration relates to DMN dysfunction. Here, we analyzed the power for different frequency bands from DMN time series extracted using a probabilistic independent component analysis (pICA) of fMRI data, in order to test the hypothesis of altered frequency power in the DMN under RS conditions. Methods: We obtained RS fMRI series (3T, 3 × 3x3 mm resolution, 45 slices, TR 2.55 s, 210 volumes) in 25 schizophrenia patients (mean age 30a ± 7.3), on stable a…
