How fast up the ladder? Factors associated with an accelerated step-up therapy in IBD-patients at early stages: Results from a population based cohort

Background: With the introduction of anti-TNF-therapies in the treatment of IBD, the therapeutic strategies have changed during the last decade from a conventional step-up management to an accelerated step-up care to avoid long-term complications and improve outcomes. Little is known about the implementation of these novel strategies into the daily care from population-based cohorts. Therefore, the aim of this study was to evaluate this question and to identify risk factors associated with the early use of immunosuppressants or anti-TNF-therapies in a population-based IBD cohort. Methods: Patients with an IBD di…