INFORM: personalized pediatric oncology enters the clinic
O Witt, DT Jones, D Capper, R Witt, C van Tilburg, A von Deimling, A Eggert, P Lichter, SM Pfister · Klinische Pädiatrie · 2014 · Heft 12
Bibliografische Angaben
Zusammenfassung
Introduction: Relapsed tumors in pediatric oncology remain a therapeutic challenge over the past decades. With the advancement of novel high throughput molecular technologies including next generation sequencing, druggableoncogenetic driver mutation can potentially be detected in a cost effective manner. We initiated INFORM (INdividualized therapy FOr Relapsed Malignancies in childhood) comprising a nation-wide consortium of several study groups of the German Society of Pediatric Oncology and Hematology (GPOH). INFORM aims to provide a population-based access forpediatric patients with relapsed high risk disease…
