PreOS (Preeclampsia Open Study), a Multicenter, Prospective, Non-Interventional Study Evaluating the Influence of the sFlt-1/PlGF Ratio on Physician Decision-Making in Pregnant Wo…
H Stepan, D Schlembach, A Ramoni, F Bahlmann, R van der Does, D Messinger, W Verhagen-Kamerbeek, M Reim, M Hund, E Klein · Geburtshilfe und Frauenheilkunde · 2015 · Heft 04
Bibliografische Angaben
Zusammenfassung
Problem statement: Preeclampsia is a major cause of maternal, fetal and neonatal morbidity/mortality. Levels of serum sFlt-1 (soluble fms-like tyrosine kinase-1) are increased and levels of serum PlGF (placental growth factor) are decreased in pregnant women developing or having diagnosed preeclampsia/eclampsia/HELLP (hemolysis, elevated liver enzymes, low platelets) syndrome. Measurement of the sFlt-1/PlGF ratio is used as additional tool in preeclampsia diagnosis. However, the utility of the sFlt-1/PlGF ratio in guiding physicians' surveillance and treatment decisions for patients with suspicion of preeclampsi…
