Treatment of PPROM with anhydramnion colonized by multi-resistant Klebsiella pneumonia with continuous amnioinfusion and antibiotic administration through subcutaneously implanted…

Bacterial infection is the main cause of preterm premature rupture of membranes (PPROM) with anhydramnion leading to preterm delivery, pulmonary hypoplasia, sepsis, and joint deformities. Expectant management, broad-spectrum antibiotics and antenatal corticosteroids are routinely used in this condition with very limited success to prevent bacteraemia, chorioamnionitis, funisitis and intra-amniotic infection syndrome. Here we report a case in which we attempted to treat the Klebsiella induced PPROM with continuous amnioinfusion and antibiotic administration through subcutaneously implanted intrauterine port syste…