Dimethylarginine serum concentrations effectively identify subjects with colorectal carcinoma
SK Eder, TK Felder, A Stadlmayr, U Huber-Schönauer, D Niederseer, W Patsch, E Aigner, C Datz · Zeitschrift für Gastroenterologie · 2015 · Heft 05
Bibliografische Angaben
Zusammenfassung
Background and Aims: Along the progression from normal colonic mucosa to colorectal cancer systemic metabolic pathways may be affected. We aimed to identify metabolic features and possible biomarkers of colorectal carcinoma and advanced adenoma. Methods: According to the results of screening colonoscopy 402 patients were allocated to one of 3 groups: colorectal carcinoma (CRC, n = 47), advanced adenoma (AA, n = 55), control (CTRL, n = 300). The serum metabolite profile of all subjects was obtained by API 4000 triple quadrupole mass spectrometer (ABSciex) using the AbsoluteIDQTM p180 kit (BIOCRATES Life Sciences)…
