Grading lymph node metastasis – a feasible approach for prognostication of stage III colorectal cancer patients

Background: The identification of parameters, which are associated with disease progression or, on the contrary, favorable outcome is an important aspect of current cancer research, since these parameters might influence patient management, in particular guide therapeutic decisions. This study aimed to assess the clinicopathological significance of tumor differentiation of metastatic lymph node tissue in AJCC/UICC stage III colorectal cancer patients. Material and Methods: The study cohort comprised 145 patients, 92 males (63%) and 53 females (37%) (ratio: 1.7: 1) with a mean age of 68.8 (median 68.4, range 40.4…