Serum Cathepsin D Levels in Pregnant Women with Gestational Diabetes Mellitus: A Case-Control Study
Umut Çağrı Gonca, Metehan Hergüner, Doğuş Budak, İbrahim Kale · Zeitschrift für Geburtshilfe und Neonatologie · 2026 · Heft 09
Bibliografische Angaben
Zusammenfassung
Abstract Objective This study aimed to evaluate maternal serum cathepsin D (CTSD) levels in pregnancies complicated by gestational diabetes mellitus (GDM) and to investigate the association between CTSD, glycemic parameters, and perinatal outcomes. Additionally, the diagnostic performance of CTSD in predicting GDM was assessed. Materials and Methods In this prospective cross-sectional case–control study, 88 pregnant women at 24–28 weeks of gestation were enrolled, comprising 44 women with GDM and 44 age-, body mass index (BMI-), and gestational age-matched healthy controls. GDM was diagnosed using a 75-g oral gl…