Amino acid and chromium enriched table water added to a standardized meal influences the glucose response depending on insulin sensitivity

Aim: To study the influence of an amino acid (AA) and chromium picolinate (CrPic) enriched table water on glucose response in healthy controls and early diabetes patients. Methods: Based on previous data from a dose response study, two double-blind crossover studies using 1,7 g AA (ile, leu, val, thr, lys) and 125 µg CrPic enriched table water were performed in Germany (early type 2 diabetes/prediabetes) and Sweden (healthy controls). The incremental area under the curve (iAUC) for glucose and insulin was documented over 180 minutes after ingestion of a standardized breakfast meal containing approximately 50 g a…