Dietary and weight loss effects on human gut microbiome diversity and metabolism
D Fangmann, FA Heinsen, DM Schulte, MC Rühlemann, K Türk, U Settgast, N Müller, W Lieb, JF Baines, S Schreiber, A Franke, M Laudes · Diabetologie und Stoffwechsel · 2016 · Heft 04
Bibliografische Angaben
Zusammenfassung
Introduction: Changes in the gut microbiome have been associated with the development of obesity. The aim of the present study was to examine (1) the effect of a formula based very-low-calorie weight loss diet (VLCD) on the gut microbiome of obese humans and (2) whether if potential changes are sustained during weight maintenance. Patients and methods: The study consisted of 3 months VLCD (approx. 800 kcal/d) followed by 3 months of weight maintenance. 18 obese humans were examined (BMI 42.3 kg/m2 (35.2 – 47.7)). A lean and an obese control group were included. Microbiome was characterized by performing high-thr…
