Fecal calprotectin in relation to established and putative systemic inflammatory biomarkers in inflammatory bowel disease – a single center experience

Introduction: Fecal calprotectin (FC) has been shown to be highly efficient in reflecting clinical and endoscopic activity, risk of relapse and postoperative recurrence of disease in patients with inflammatory bowel diseases (IBD). Traditionally systemic inflammatory serum biomarkers are commonly used for monitoring. The aim of this study was to further investigate the relation of FC as an unique fecal biomarker in relation to established and putative systemic biomarkers in Crohn's disease (CD) and ulcerative colitis (UC). Methods: Over a five year period FC, CRP, ESR, leucocytes, neutrophil-to-lymphocyte ratio,…