MRI and CT phenotyping of 600 subjects from the German COPD trial COSYCONET: study concept and current status
B Jobst, C Melzig, J Biederer, K Burmester, S Triphan, J Schliebus, I Fellhauer, A Karch, CP Heussel, HU Kauczor · Pneumologie · 2016 · Heft 07
Bibliografische Angaben
Zusammenfassung
Introduction: Imaging allows for precise characterization of regional lung alterations in COPD beyond global parameters such as spirometry. Since MRI allows for radiation-free regional morphological and functional assessment of the lung, it is the aim of this multi-centre study (ClinicalTrials.gov identifier NCT02629432) to evaluate sensitivity and specificity of morpho-functional MRI to diagnose emphysema-and airway-phenotypes of COPD, with CT as standard of reference. Methods: Prospective lung imaging is being performed in a subcohort of 600 participants from COSYCONET, the national COPD Cohort. CT and MRI dat…
