Maternal Serum Periostin as a Potential Biomarker for Gestational Diabetes Mellitus and Adverse Perinatal Outcomes
Semra Eroglu, Neset Gumusburun, Sebati Sinan Urkmez, Yeşim Civil Ürkmez, Samettin Çelik, Kübra Şahin · Zeitschrift für Geburtshilfe und Neonatologie · 2026 · Heft 05 · S. 419-424
Bibliografische Angaben
Zusammenfassung
Abstract Objective To investigate whether maternal serum periostin levels measured in the second trimester can serve as a biomarker for gestational diabetes mellitus (GDM) and predict perinatal outcomes. Methods This prospective case–control study included 173 pregnant women (103 with GDM and 70 healthy controls). Serum periostin levels were measured between 15–20 weeks of gestation. GDM was diagnosed using a 75-g oral glucose tolerance test at 24–28 weeks. Receiver operating characteristic (ROC) analysis and logistic regression were used to evaluate diagnostic performance. Results Serum periostin levels were si…
