Genetics, management and clinical outcomes in familial exudative vitreoretinopathy (FEVR): a multicentre retrospective cohort
Monica Hu, Tsveta Ivanova, Assad Jalil, Panagiotis Sergouniotis, Graeme Black, Sui Chien Wong, Chetan K. Patel, Robert Henderson, Kanmin Xue · Klinische Monatsblätter für Augenheilkunde · 2026 · Heft 10
Bibliografische Angaben
Zusammenfassung
ABSTRACT in English Background Familial exudative vitreoretinopathy (FEVR) is a group of inherited retinal diseases characterised by abnormal retinal angiogenesis and peripheral non-perfusion. While over 10 genes have been implicated in FEVR, genotype-phenotype correlations and their clinical significance are incompletely understood. Here we describe a retrospective cohort of FEVR patients and assess the impact of defined genetic variants on protein structure, disease severity, inter-ocular variability, as well as treatment choices and visual outcomes. Methods Retrospective cohort of 51 patients with FEVR across…
